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KMID : 0360220160570030518
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Journal of the Korean Ophthalmological Society
2016 Volume.57 No. 3 p.518 ~ p.523
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A Case of Steroid Glaucoma in a Child Treated with Systemic Steroid as Graft-Versus-Host Disease
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어두리:Eo Doo-Ri
한종철:Han Jong-Chul/기창원:Kee Chang-Won
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Abstract
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Purpose: To report a case of steroid-induced glaucoma in a child who was treated with systemic steroids for a long period due to graft-versus-host disease.
Case summary: A 10-year-old male was referred to our ophthalmologic clinic for examination of papilledema due to persistent headache and nausea. He was diagnosed as aplastic anemia 8 years prior and took approximately 4,000 mg of oral prednisolone for 8 years from April 2007 to April 2015 for treatment of lung graft-versus-host disease after hematopoietic stem cell transplantation. His best corrected visual acuity was 0.8 (decimal) in the right eye, 0.5 in the left eye and intraocular pressure (IOP) measured using a Goldmann applanation tonometer was 42 mm Hg in the right eye and 43 mm Hg in the left eye. His cup-to-disc ratio was 0.8 in the right eye and 0.7 in the left eye. Additionally, superior and inferior neuroretinal rim thinning was present in both eyes. Despite using IOP-lowering agents, IOP was not controlled. However, after trabeculectomy with mitomycin C in both eyes, IOP became normalized.
Conclusions: In cases of pediatric patients treated with systemic steroids for a long period of time, regular observation is necessary to prevent IOP elevation and steroid-induced glaucoma.
J Korean Ophthalmol Soc 2016;57(3):518-523
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KEYWORD
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Oral prednisolone, Steroid-induced glaucoma, Systemic steroid
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